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KMID : 0370220030470050283
Yakhak Hoeji
2003 Volume.47 No. 5 p.283 ~ p.287
Synthesis of Quinolone Analogs of Isoflavonoids
Àü¶ó¿Á/Jeon RO
ÀÌÁöÇý/Á¤»óÇå/Lee JH/Jung SH
Abstract
Isoflavonoids are abundant in natural products and reported with many synthetic variations. However, relatively few quinolone analogs of isoflavonoids have been described. As part of our endeavor to pursue biologically active novel isoflavonoids, we report an efficient synthetic route for quinolone analogs of isoflavonoids. The key intermediate, 2¡¯-aminochalcone 2 was obtained from substituted aniline and cyclized to afford quinolones 6, 8a, and 8b.
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